OBTAINING NITROGEN CONTAININ DIKARBOKSILAT

Abstract

We have conducted research into the synthesis and analysis of nellylated-indazole compounds. These compounds were produced through a process involving substituted hydroxycyclohexanones, hydrazine hydrate, and phenacyl bromide. Our investigation revealed that, depending on the specific structure of the compounds involved, the reaction can proceed via both nitrogen and oxygen alkylation pathways. The examination of the reactions between 2,6- dicarboxylates and amine derivative hydrochlorides revealed a novel finding: the employment of potassium carbonate as a base facilitates the desired direction of heterocyclization for the first time. On the basis of 3-component condensation, diacetyl (diet-oxycarbonyl) substituted hydroxycyclohexanones with thiosemi-derivatives and bromide were obtained. Based on the results, methods of obtaining derivative dicarboxylates were developed, and the structure of the latter depends on electrophilic activity. The structural characteristics of all obtained derivatives were studied and the structures were proved by the method of rengonostructural analysis.